...Inflammation Is the Result of a Multi-faceted ProcessHormonal changes are at the root of acne pathogenesis.The primary target of acne is the pilosebaceous unit of the follicle.Hormones stimulate increased production of lipids in the follicle.Inflammation probably arises from the presence of prostaglandins and cytokines that are attracted to the lipids within the follicle.Some individuals may be genetically prone to overactive inflammatory pathways, which increases their chances of having severe inflammatory acne....»
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«...It is difficult to determine the exact cause of acne. Doctors have postulated many different and varying causes. What they agree on however is the fact that, first, hormones are a big part in the appearance of acne. In a person's teenage years, male hormones called testosterone are often overproduced by the body, causing the body's sebaceous glands to generate more oil. Dead skin cells combine with the oil or sebum in the face clogging the pores and resulting to comedones (whiteheads) or blackheads. Later on, these can aggravate and become painful pimples....»
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